The incident happened on Mud Creek Road, about a mile from the Route 1 intersection.
A Department of Public Safety spokesman said 67-year-old Terry Bragdon of Lamoine was walking in dark clothing when he was hit by a pickup truck and killed.
Amy Metcalf, 47, of Milbridge was driving the truck. She and her passenger were not injured.
Mud Creek Road was closed for hours Wednesday as police investigated the accident.