Maine Drug Enforcement Agency investigators also arrested 26-year-old David Jones of Bronx, New York, 32-year-old Chuckie Langley of New York, New York, and Holly Inman, 41, of Machias.
All three face charges of selling illegal drugs, including cocaine and heroin.
According to a spokesman for the Maine Department of Public Safety, the traffic stop was the result of information agents gathered during an investigation.
Police say they believe the drugs were heading to Washington County.
The men from New York are being held without bail, while bail for Inman has been set at $35,000 dollars.