The kayak and canoe event is part of the Eastern Maine Medical Center Champion the Cure Challenge, which raises money for cancer care.
Participants started on the Brewer waterfront and paddled to the Interstate 395 bridge and back.
Event organizers said well over 100 people came out for this event, which was for a cause that many people have a connection to.
This was the first year the paddle fundraiser was held.
"Everyone can identify with the importance of it and some personal connection to cancer," organizer Clayton Cole said. "You don't have to be an expert paddler to do this, so look at the fun these people are having today and consider joining us next year."
The fundraising goal was around $20,000 and before Saturday's event got underway, organizers said they were three-quarters of the way to that goal.