A search warrant was carried out around 6:30 p.m. Thursday at a home on Harriman Road in Swanville.
Authorities said they found Christopher King, 30, in the process of weighing and packaging heroin for resale.
They also found about 14 grams of heroin, along with packaging materials and cash.
Three other people were also arrested when they arrived in a car.
Officials say they found 30 grams of crack and 5 grams of cocaine inside the vehicle.
King and Taylor Andrews, 28, of Gardiner both were charged with trafficking in either crack or heroin.
Bobby Dean Berry, Sean Rohan and Princessayana Harris of New York also were charged with drug trafficking.