State police said the victim was driving a transport van when he was struck from behind by an SUV on Route 202.
The impact sent the van hurdling several hundred yards down the road where it went down an embankment and crashed into a stand of trees.
Richard Charest of Winthrop, 59 was killed in the crash. He had been transporting a body back to a funeral home when the accident happened around 6:00 p.m.
The SUV was operated by Donald Asselin, 58, of Sabattus. He has minor injuries.
Police are now trying to figure out what caused Asselin to slam into the back of the van and hope to hear from anyone who witnessed the crash.