This will be Gasol's 13th missed game this year, fifth with the concussion.
The Lakers expect to start Earl Clark in his place alongside Dwight Howard, who returned on Sunday after being out with a shoulder injury.
Gasol has played in 25 games this season. The Lakers record in that stretch is 12-13 (48%), better than the team's overall 16-21 (43.2%) on the season.
Gasol will be re-evaluated throughout the week.
The Miami Heat will visit Staples Center on Thursday before the Lakers head out on a three-game road trip.