Biden will give the commencement address on Sunday to 481 graduates and their families.
The college posted a message on their Facebook page telling everyone to keep an eye out for Biden.
With preparations underway at the Waterville campus, excitement is building, but students said it's bittersweet.
Senior Lucas lam said "I'm really gonna miss this place a lot, when Sunday comes I'm actually extremely excited to see Joe Biden."
Lam added he's looking forward to hearing what Biden has to say, especially after getting a selfie with him at an event two years ago.